FAST-PGX

Pharmacogenomics (PGX)

What Is a PGX Test?

Pharmacogenetic (PGX) testing is an informative dive into a person’s DNA, specifically investigating the DNA of CYP proteins that are involved in the metabolism of medications. This genetic information can inform a physician and patient on their ability to process and respond to drugs. With this analysis, physicians can tailor medication regimen and dosing plans to an individual’s specific needs thereby increasing effectiveness of medications while greatly reducing the risk of adverse drug effects (AE’s).

  • Results in as little as 7 days.

  • Comprehensive PGX report that discusses a wide range of medications and identified clinical risk.

  • Only requires a cheek swab, minimally invasive.


What Can PGX Tell Us?

PGX testing define whether a person is a fast, normal, or slow metabolizer of drugs. Drug metabolism rates have massive effects on how the patient responds to the drug including:

TOXICITY This test can identify risks of accumulation of drug in the blood stream. Excessive concentrations of drugs can lead to an increased risk of adverse drug effects and unwanted drug reactions.

HYPERSENSITIVITY Normal amounts of the drug enter the bloodstream, due to slow metabolism rates, the length of time the drug is in the body is increased which in turn raises the risk for unwanted drug reactions.

LACK OF EFFICACY The metabolism rates are so high that the drug is not able to achieve the minimum required concentration for drug effect and therefore the patient has no beneficial response to the drug.


BENEFITS OF TESTING

  • MINIMIZE COST
    PGX testing can help physicians make better prescription choices earlier in treatment.

  • REDUCE RISK OF ADVERSE DRUG REACTIONS
    PGX testing can identify drug classes of risk to the patient and help physicians avoid prescribing those drugs to patients.

  • OPTIMIZE MEDICATION PLANS
    Creating a drug treatment plan that best matches a patient’s metabolic profile can now be achieved with data learned from PGX testing.


WHY USE PGX

Research shows that over 90% of people carry at least one PGX response element and 65% of people are exposed to a drug that is mismatched to at least one marker gene. Thus, PGX testing can have real impacts on 1 out of every 2 patients taking prescription medications. With PGX testing, you can also reduce the instances of trial-and-error prescribing methods, greatly reducing the chance for adverse drug reactions to new prescriptions.

SAMPLE IMPACTED MEDICATIONS
AND GENES TESTED